The Genitourinary (GU) pathology service at UMass Memorial  Medical Center provides skilled interpretation of specimens from the prostate, urinary bladder, kidney and testis.   Our GU pathology section serves the UMass Memorial Medical Center and urology practices in Massachusetts and Connecticut.  We have developed a novel molecular diagnostic technique combining cytology and fluorescent in situ hybridization (FISH) analysis, a cutting edge technology for the diagnosis of urothelial carcinoma. We utilize an array of immunohistochemical and molecular biological techniques in the evaluation of pathological diagnostic problems.

Our major research focus is the identification and validating novel biomarkers for diagnostic and prognostic use. Alpha-methylacyl-coenzyme A racemase (AMACR/P504S), a molecular diagnostic biomarker for prostate cancer that Dr. Jiang first described in 2001, now assists pathologists around the world accurately diagnose prostate cancer in prostate needle biopsies.  Recently, we discovered IMP3, a new molecular marker that allows patients and clinicians to get an accurate prediction of the metastatic potential or progression of renal cell carcinoma and superficial bladder cancer